Iontophoresis Amplifier
The fast systems comes with a headstage for each channel. This allows to integrate a capacitance compensation circuitry and resistance measurement. If you need application pulses in the range of a few ms or even below for very focal application, this is the system of choice.
The slower system doesn’t have headstages and capacitance compensation. It is suitable when timing is not an issue (e.g. bulk loading).
The balance channel injects the same amount of current into the sample as the application channel(s) – with opposite polarity. This way the overall charge of the sample remains unchanged. This is especially useful, if parallel recordings are performed, where DC shifts would impair the measurement (e.g. patch clamp).
For 98% of the experiment the 45 V system is fully sufficient. The 150 V system should only be used, if large current are necessary and even possible. Remember that even npi’s instruments can’t cheat Ohm’s law.
Example: 150 V into a 1 MΩ electrode will generate a current of 150 µA.
| Part No. | Description |
| MVCS-01-45 | MVCS-01-45V 19″ Iontophoresis System |
| MVCS-01C-45 | MVCS-01C-45V 19″ Iontophoresis System (with balance) |
| MVCS-01U-45 | 2nd Channel Upgrade f. MVCS-01-45 System (19″) |
| MVCC-U-45 | Balance Upgrade f. MVCS-45 System (19″) |
| MVCS-02-45 | MVCS-02-45V 19″ Iontophoresis System |
| MVCS-02C-45 | MVCS-02C-45V 19″ Iontophoresis System (with balance) |
| MVCS-01-150 | MVCS-01-150V 19″ Iontophoresis System |
| MVCS-01C-150 | MVCS-01-C-150V 19″ Iontophoresis System (with balance) |
| MVCS-01U-150 | 2nd Channel Upgrade f. MVCS-01-150 System (19″) |
| MVCC-U-150 | Balance Upgrade f. MVCS-150 System (19″) |
| MVCS-02-150 | MVCS-02-150V 19″ Iontophoresis System |
| MVCS-02C-150 | MVCS-02-C-150V 19″ Iontophoresis System (with balance) |
| MVCS-C-01-45 | MVCS-C-01-45V 19″ Iontophoresis System |
| MVCS-C-01C-45 | MVCS-C-01C-45V 19″ Iontophoresis System (with balance) |
| MVCS-C-01U-45 | 2nd Channel Upgrade f. MVCS-C-01C-45 |
| MVCC-C-U-45 | Balance Upgrade f. MVCS-C-45 System (19″) |
| MVCS-C-02-45 | MVCS-C-02-45V 19″ Iontophoresis System |
| MVCS-C-02C-45 | MVCS-C-02C-45V 19″ Iontophoresis System (with balance) |
| MVCS-C-01-150 | MVCS-C-01-150V 19″ Iontophoresis System |
| MVCS-C-01C-150 | MVCS-C-01-C-150V 19″ Iontophoresis System (with balance) |
| MVCS-C-01U-150 | 2nd Channel Upgrade f. MVCS-C-01C-150 System (19″) |
| MVCC-C-U-150 | Balance Upgrade f. MVCS-C-150 System (19″) |
| MVCS-C-02-150 | MVCS-C-02-150V 19″ Iontophoresis System |
| MVCS-C-02C-150 | MVCS-C-02-C-150V 19″ Iontophoresis System (with balance) |
| MVCS-01M-45 | MVCS-01M-45V Module for EPMS-H |
| MVCS-01M-150 | MVCS-01M-150V Module for EPMS-H |
| MVCS-02M-45 | MVCS-02M-45V Module for EPMS-H |
| MVCS-02M-150 | MVCS-02M-150V Module for EPMS-H |
| MVCC-M-45 | Balance Module f. MVCS-45 System (EPMS-H) |
| MVCC-M-150 | Balance Module f. MVCS-150 System (EPMS-H) |
| MVCS-C-01M-45 | MVCS-C-01M-45V Module for EPMS-H |
| MVCS-C-01M-150 | MVCS-C-01M-150 V Module for EPMS-H |
| MVCS-C-02M-45 | MVCS-C-02M-45V Module for EPMS-H |
| MVCS-C-02M-150 | MVCS-C-02M-150V Module for EPMS-H |
| MVCC-C-M-45 | Balance Module f. MVCS-C-45 System (EPMS-H) |
| MVCC-C-M-150 | Balance Module f. MVCS-C-150 System (EPMS-H) |
| MVCS-HS-150 | Headstage for MVCS-150 Systems |
| MVCS-HS-45 | Headstage for MVCS-45 Systems |
| MVCS-EH | Standard Micro Electrode Holder |
| MODE of operation: | set with two toggle switches, EJECT / RETAIN / AUTO switch enables manual or TTL controlled operation SET / OPERATE switch connects automatically electrode outputs to an internally grounded load, to make possible well defined presetting (SET position) COMPENSATE / OFF / EXTERN switch (balance unit), selects compensation signal or connects balance module to external signal source (additional channel). |
| HEADSTAGES | Size (approx.): Standard 70x30x25 mm, holding bar diameter 8 mm, length 150 mm (±15 V, ±45 V), optional: 100x50x20 mm (± 150V) or 225x40x60mm (± 225V). Electrode connector: BNC connector, (headstage with driven shield also available). Ground connector: 2.4 mm connector. Electrode output: floating current source, output impedance >1012 Ω |
| ELECTRODE RESISTANCE TEST | 1 mV / MΩ at the voltage monitor Vel / 10, obtained by application of square current pulses, ±10 nA from built-in pulse generator. |
| EJECT | ten-turn control, switch selected range max. 1 µA / 100 nA. |
| RETAIN | ten-turn control, max. 100 nA. |
| CAPACITY COMPENSATION | range 0 30 pF, ten-turn control. |
| MAXIMUM CURRENT | 150 nA (±15 V), 450 nA (±45 V standard voltage), 1.5 µA (±150 V) into 100 MΩ load. Other ranges available on request. OUTPUT CURRENT POLARITY: selected by INVERTED / NORMAL toggle switch. BALANCE OUTPUT (MVCS-X-02C-45, MVCC): inverted sum of all currents, sensitivity 1 µA / V, for connecting external balance module. |
| TTL INPUT (AUTO mode): | LO = RETAIN, HI = EJECT, isolated, Rin > 5 kΩ |
| ANALOG INPUT | sensitivity 100 nA / V, Rin > 100 kΩ, range ±10 V. |
| CURRENT MONITOR | sensitivity 100 nA / V, Rout = 250 Ω, not isolated. |
| VOLTAGE MONITOR | Vel / 10, Rout = 250 Ω, not isolated. |
| DISPLAY | current XXXX nA, balance current XX.XX µA, voltage XXX.X V, REL XXXX MΩ, separate displays for each channel, displayed value is set by a three position toggle switch. OVER LEDs: activated 10 % below maximum current. |
| POWER REQUIREMENTS | 115 / 230 V AC, 45 – 60 W. |
| DIMENSIONS | 19″ cabinet, 19“ (483 mm), x 10″ (250 mm) x 3.5″ (88 mm). |
| Manual | MVCS manual |
| Brochure | Drug Application |
In principle, MVCS systems are available as:
Fast systems (MVCS-C-02C) are delivered with headstages, ground connector, a power cord and a user manual.
Slower systems (MVCS-02C) are delivered with connectors for electrode connection and ground, a power cord and a user manual (without headstages).
Standard voltage ranges are ±45 V or ±150 V. Other ranges are available on request.
NOTE: All MVCS systems are also available as one-channel versions and one-channel versions can be ugraded to two channels. Furthermore, all version can also be ordered without a balance channel.
Please contact npi electronic or your distributor for details.
Look at the “MVCS Models” tab below for all options. Customized configurations are possible, please contact npi electronic.
The MVCS is also available as module for the EPMS-07 system.
The fast systems comes with a headstage for each channel. This allows to integrate a capacitance compensation circuitry and resistance measurement. If you need application pulses in the range of a few ms or even below for very focal application, this is the system of choice.
The slower system doesn’t have headstages and capacitance compensation. It is suitable when timing is not an issue (e.g. bulk loading).
The balance channel injects the same amount of current into the sample as the application channel(s) – with opposite polarity. This way the overall charge of the sample remains unchanged. This is especially useful, if parallel recordings are performed, where DC shifts would impair the measurement (e.g. patch clamp).
For 98% of the experiment the 45 V system is fully sufficient. The 150 V system should only be used, if large current are necessary and even possible. Remember that even npi’s instruments can’t cheat Ohm’s law.
Example: 150 V into a 1 MΩ electrode will generate a current of 150 µA.
| Part No. | Description |
| MVCS-01-45 | MVCS-01-45V 19″ Iontophoresis System |
| MVCS-01C-45 | MVCS-01C-45V 19″ Iontophoresis System (with balance) |
| MVCS-01U-45 | 2nd Channel Upgrade f. MVCS-01-45 System (19″) |
| MVCC-U-45 | Balance Upgrade f. MVCS-45 System (19″) |
| MVCS-02-45 | MVCS-02-45V 19″ Iontophoresis System |
| MVCS-02C-45 | MVCS-02C-45V 19″ Iontophoresis System (with balance) |
| MVCS-01-150 | MVCS-01-150V 19″ Iontophoresis System |
| MVCS-01C-150 | MVCS-01-C-150V 19″ Iontophoresis System (with balance) |
| MVCS-01U-150 | 2nd Channel Upgrade f. MVCS-01-150 System (19″) |
| MVCC-U-150 | Balance Upgrade f. MVCS-150 System (19″) |
| MVCS-02-150 | MVCS-02-150V 19″ Iontophoresis System |
| MVCS-02C-150 | MVCS-02-C-150V 19″ Iontophoresis System (with balance) |
| MVCS-C-01-45 | MVCS-C-01-45V 19″ Iontophoresis System |
| MVCS-C-01C-45 | MVCS-C-01C-45V 19″ Iontophoresis System (with balance) |
| MVCS-C-01U-45 | 2nd Channel Upgrade f. MVCS-C-01C-45 |
| MVCC-C-U-45 | Balance Upgrade f. MVCS-C-45 System (19″) |
| MVCS-C-02-45 | MVCS-C-02-45V 19″ Iontophoresis System |
| MVCS-C-02C-45 | MVCS-C-02C-45V 19″ Iontophoresis System (with balance) |
| MVCS-C-01-150 | MVCS-C-01-150V 19″ Iontophoresis System |
| MVCS-C-01C-150 | MVCS-C-01-C-150V 19″ Iontophoresis System (with balance) |
| MVCS-C-01U-150 | 2nd Channel Upgrade f. MVCS-C-01C-150 System (19″) |
| MVCC-C-U-150 | Balance Upgrade f. MVCS-C-150 System (19″) |
| MVCS-C-02-150 | MVCS-C-02-150V 19″ Iontophoresis System |
| MVCS-C-02C-150 | MVCS-C-02-C-150V 19″ Iontophoresis System (with balance) |
| MVCS-01M-45 | MVCS-01M-45V Module for EPMS-H |
| MVCS-01M-150 | MVCS-01M-150V Module for EPMS-H |
| MVCS-02M-45 | MVCS-02M-45V Module for EPMS-H |
| MVCS-02M-150 | MVCS-02M-150V Module for EPMS-H |
| MVCC-M-45 | Balance Module f. MVCS-45 System (EPMS-H) |
| MVCC-M-150 | Balance Module f. MVCS-150 System (EPMS-H) |
| MVCS-C-01M-45 | MVCS-C-01M-45V Module for EPMS-H |
| MVCS-C-01M-150 | MVCS-C-01M-150 V Module for EPMS-H |
| MVCS-C-02M-45 | MVCS-C-02M-45V Module for EPMS-H |
| MVCS-C-02M-150 | MVCS-C-02M-150V Module for EPMS-H |
| MVCC-C-M-45 | Balance Module f. MVCS-C-45 System (EPMS-H) |
| MVCC-C-M-150 | Balance Module f. MVCS-C-150 System (EPMS-H) |
| MVCS-HS-150 | Headstage for MVCS-150 Systems |
| MVCS-HS-45 | Headstage for MVCS-45 Systems |
| MVCS-EH | Standard Micro Electrode Holder |
| MODE of operation: | set with two toggle switches, EJECT / RETAIN / AUTO switch enables manual or TTL controlled operation SET / OPERATE switch connects automatically electrode outputs to an internally grounded load, to make possible well defined presetting (SET position) COMPENSATE / OFF / EXTERN switch (balance unit), selects compensation signal or connects balance module to external signal source (additional channel). |
| HEADSTAGES | Size (approx.): Standard 70x30x25 mm, holding bar diameter 8 mm, length 150 mm (±15 V, ±45 V), optional: 100x50x20 mm (± 150V) or 225x40x60mm (± 225V). Electrode connector: BNC connector, (headstage with driven shield also available). Ground connector: 2.4 mm connector. Electrode output: floating current source, output impedance >1012 Ω |
| ELECTRODE RESISTANCE TEST | 1 mV / MΩ at the voltage monitor Vel / 10, obtained by application of square current pulses, ±10 nA from built-in pulse generator. |
| EJECT | ten-turn control, switch selected range max. 1 µA / 100 nA. |
| RETAIN | ten-turn control, max. 100 nA. |
| CAPACITY COMPENSATION | range 0 30 pF, ten-turn control. |
| MAXIMUM CURRENT | 150 nA (±15 V), 450 nA (±45 V standard voltage), 1.5 µA (±150 V) into 100 MΩ load. Other ranges available on request. OUTPUT CURRENT POLARITY: selected by INVERTED / NORMAL toggle switch. BALANCE OUTPUT (MVCS-X-02C-45, MVCC): inverted sum of all currents, sensitivity 1 µA / V, for connecting external balance module. |
| TTL INPUT (AUTO mode): | LO = RETAIN, HI = EJECT, isolated, Rin > 5 kΩ |
| ANALOG INPUT | sensitivity 100 nA / V, Rin > 100 kΩ, range ±10 V. |
| CURRENT MONITOR | sensitivity 100 nA / V, Rout = 250 Ω, not isolated. |
| VOLTAGE MONITOR | Vel / 10, Rout = 250 Ω, not isolated. |
| DISPLAY | current XXXX nA, balance current XX.XX µA, voltage XXX.X V, REL XXXX MΩ, separate displays for each channel, displayed value is set by a three position toggle switch. OVER LEDs: activated 10 % below maximum current. |
| POWER REQUIREMENTS | 115 / 230 V AC, 45 – 60 W. |
| DIMENSIONS | 19″ cabinet, 19“ (483 mm), x 10″ (250 mm) x 3.5″ (88 mm). |
| Manual | MVCS manual |
| Brochure | Drug Application |
