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Microinjection System

Drug application devices

Our substance application systems convince through quality, versatility and price. npi electronic is one of the leading manufacturers of microinjectors, pressure injectors, applicators and electroporators. We also distribute many devices from well-known manufacturers. Read more…

Your benefits:

  • Fast and precise pressure microinjection
  • Iontophoresis amplifier for fast time resolution and precise spatial resolution for ejection of charged substances
  • Stand-alone single cell electroporator for fast and accurate transfection and electroporation of single cells

Frequently asked questions (FAQ):

Which device can I use to inject picolitres and femtolitres precisely?

Our PDES series is very well suited for the highly precise injection and application of pico and femtolitres. It is the apparatus for intracellular microinjection and extracellular dispense of liquids in extremely small volumes (see doi:10.1038/nprot.2006.58 and https://doi.org/10.3390/mi12010094)

How can I inject a charged substance or liquid through a pipette?

The iontophoreses suitable for this purpose work with small and precise electric shocks that are delivered to the filled pipette. This ejection current ensures the application of the drug. The high voltage required for this is only supplied by the npi electronic devices, which function with up to 150V (see doi:10.3791/50701).

I have often heard the term PicoSpritzer, where can I buy these devices?

The PicoSpritzer is a device that has defined the name for a whole category of microinjectors. Unfortunately, it has been discontinued, but there are pressure microinjectors from several manufacturers. The PDES series from npi electronic is one of them.

What can I use to electroporate and transfect individual cells?

The Electroporator (or ElPorator) from npi electronic is a device that is ideally suited for electroporating and transfecting single cells. It is a stand-alone device that can be used in combination with the DigiStim in any laboratory without additional equipment. It is best suited for high throughput single cell electroporation.

How can I stimulate the whiskers of my laboratory animal?

The PDES series is best suited for puffing against the whiskers to excite rodents. The quiet valve helps to ensure that no disturbance occurs during behavioral experiments.

What is the spatial precision of iontophoretic applications?

The MVCS series iontophoresis amplifiers from npi can be equipped with headstages with capacity compensation. This allows for applying very short and precise pulses (< 1 ms) which result in a high local resolution of ~1 µm³ – enough for targeting single synaptic boutons.