Our substance application systems convince through quality, versatility and price. npi electronic is one of the leading manufacturers of microinjectors, pressure injectors, applicators and electroporators. We also distribute many devices from well-known manufacturers. Read more…
Our PDES series is very well suited for the highly precise injection and application of pico and femtolitres. It is the apparatus for intracellular microinjection and extracellular dispense of liquids in extremely small volumes (see doi:10.1038/nprot.2006.58 and https://doi.org/10.3390/mi12010094)
The iontophoreses suitable for this purpose work with small and precise electric shocks that are delivered to the filled pipette. This ejection current ensures the application of the drug. The high voltage required for this is only supplied by the npi electronic devices, which function with up to 150V (see doi:10.3791/50701).
The PicoSpritzer is a device that has defined the name for a whole category of microinjectors. Unfortunately, it has been discontinued, but there are pressure microinjectors from several manufacturers. The PDES series from npi electronic is one of them.
The Electroporator (or ElPorator) from npi electronic is a device that is ideally suited for electroporating and transfecting single cells. It is a stand-alone device that can be used in combination with the DigiStim in any laboratory without additional equipment. It is best suited for high throughput single cell electroporation.
The PDES series is best suited for puffing against the whiskers to excite rodents. The quiet valve helps to ensure that no disturbance occurs during behavioral experiments.
The MVCS series iontophoresis amplifiers from npi can be equipped with headstages with capacity compensation. This allows for applying very short and precise pulses (< 1 ms) which result in a high local resolution of ~1 µm³ – enough for targeting single synaptic boutons.